FLUORESCENT-PROTEIN STABILIZATION AND HIGH-RESOLUTION IMAGING OF CLEARED, INTACT MOUSE BRAINS.

In order to observe and quantify long-range neuronal connections in intact mouse brain by light microscopy, it is first necessary to clear the brain, thus suppressing refractive-index variations.Here we describe a method that clears the brain and preserves the signal from Swim proteinaceous fluorophores using a pH-adjusted non-aqueous index-matchin

Fungal keratitis is an infectious disease of the cornea.Lack of suspicion and delayed diagnosis herald the onset of complications often leading to permanent MLB Boxes loss of vision or worse, enucleation.While a variety of pathogenic fungi especially non-dermatophyte molds associated with fungal keratitis have been identified, a comprehensive revie